We recommend that you use IMAP with your client, since you will be able to access your mail from the CalMail web interface as well as from IMAP clients you have configured on any number of computers.
The general client settings for CalMail are:
TLS or SSL is required for all connections. If your account is in a domain other than berkeley.edu (i.e. email@example.com), you will need to use your full email address as your username. Only your primary account name, not any aliases you might have, may be used to log in.